Liverpool will make a late decision on Steven Gerrard, who missed England duty because of a groin problem.
Martin Kelly should feature despite an ankle injury but Martin Skrtel is doubtful with a thigh problem, and Jonjo Shelvey is out for three months.
Wigan defender Gary Caldwell could play with a mask to protect the cheekbone he fractured earlier this month.
Republic of Ireland midfielder James McCarthy, who missed international duty to rest his ankle, should be available.
Liverpool
Doubtful: Cole (knee), Gerrard (groin), Kelly (ankle), Skrtel (thigh)
Injured: Carroll (thigh), Shelvey (knee), Spearing (foot)
Wigan
Doubtful: G Caldwell (fractured cheekbone), Figueroa (hamstring)